Eimeria praecox: a brief story of the big unknown of coccidiosis in poultry

Seven species of Eimeria (E. acervulina, E. brunetti, E. maxima, E. mitis, E. necatrix, E. praecox and E. tenella) are recognized to be causative agents of coccidiosis in chickens of the genus Gallus gallus. Until recently, Eimeria praecox was considered to be a non-pathogenic species unable to cause adverse effects in the host.

E.-praecox-in-the-duodenum

In fact, in 1970, when Johnson & Reid wrote the milestone article that for the first time standardized and described the scoring scale for lesions caused by all Eimeria spp., Eimeria praecox was not included. It was, and still is, well know that E. praecox is not able to provoke pathognomonic lesions like E. acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella, however even then some researchers were investigating whether this species of Eimeria was truly non-pathogenic.

Continue reading Eimeria praecox: a brief story of the big unknown of coccidiosis in poultry

Eimeria immunogenicity, basic information and protection conferred by a precocious line of Eimeria necatrix.

Eimeria spp is a protozoan parasite with a complex life cycle and so is the host immune response to Eimeria infection. In the last decade, huge progress has been made in the identification of host and parasite genes involved in immunogenicity but there are still some immunity mechanisms to be discovered.

 

As a general rule, we say that Eimeria immunity is species-specific, meaning that each species of Eimeria is able to stimulate protective immunity against itself. Although some studies suggest that partial cross-protection can be achieved (Augustine et al. 1991), from a practical perspective we have to assume the widely accepted belief that there is no cross-protection between species.

Continue reading Eimeria immunogenicity, basic information and protection conferred by a precocious line of Eimeria necatrix.

Eimeria biological cycle: an example of perfect complexity in biology

The Eimeria biological cycle is a very complex one and is comprised of intracellular, extracellular, asexual and sexual stages. It is of paramount importance its understanding as its comprehension helps to understand the parasite epidemiology in the field, its pathogenicity and immunobiology.

 

Seven species of Eimeria (E. acervulina, E. brunetti, E. maxima, E. mitis, E. necatrix, E. praecox and E. tenella) are recognized to be causative agents of coccidiosis in chickens of the genus Gallus gallus.

Continue reading Eimeria biological cycle: an example of perfect complexity in biology